PDPK1 anticorps (AA 506-556)

N° du produit ABIN7452710

L’anticorps anti-PDPK1 Polyclonal Lapin est utilisé pour la détection de PDPK1 dans des échantillons de Humain et Souris. Il a été validé pour WB et IP.

Aperçu rapide pour PDPK1 anticorps (AA 506-556) (ABIN7452710)

Antigène: PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDPK1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-PDPK1 anticorps

Épitope: AA 506-556

Fonction: Rabbit anti-PDK1 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 506 and 556

Isotype: IgG

Information d'application

Indications d'application:

IP: 5 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur PDPK1

Antigène: PDPK1 (3-phosphoinositide Dependent Protein Kinase-1 (PDPK1))

Autre désignation: PDK1

Sujet: Background: PDK1 (3-phosphoinositide-dependent kinase-1) is a serine/threonine kinase that contains a PH domain for binding of phosphatidylinositols (PtdIns). PDK1 phosphorylates PKB/AKT in response to agonist stimulation of phosphoinositide 3-kinases (PI3Ks). Stimulation of PI3Ks generates specific inositol lipids that are important for activation of PDK1. PDK1 may also be responsible for phosphorylating PKA, PKC-zeta, RPS6KA1, and RPS6KB1.

ID gène: 5170

NCBI Accession: NP_002604

UniProt: O15530

Pathways: Signalisation PI3K-Akt, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Regulation of Cell Size, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals