LAT anticorps (AA 212-262)

N° du produit ABIN7452825

Cet anticorps anti-LAT est un anticorps Lapin Polyclonal détectant LAT dans WB et IP. Adapté pour Humain.

Aperçu rapide pour LAT anticorps (AA 212-262) (ABIN7452825)

Antigène: LAT (Linker For Activation of T Cells (LAT))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LAT est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-LAT anticorps

Épitope: AA 212-262

Fonction: Rabbit anti-LAT Antibody, Affinity Purified

Homologie: Mouse,Rat

Purification: Affinity Purified

Immunogène: between AA 212 and 262

Isotype: IgG

Information d'application

Indications d'application:

IP: 50-100 μL/mg lysate

WB: 1:10,000 - 1:25,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur LAT

Antigène: LAT (Linker For Activation of T Cells (LAT))

Autre désignation: LAT

Sujet: Background: LAT is required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules. [taken from the Universal Protein Resource (UniProt) O43561].

ID gène: 27040

UniProt: O43561

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway