Cyclin C anticorps (AA 233-283)

N° du produit ABIN7453580

L’anticorps Lapin Polyclonal anti-Cyclin C a été validé pour WB, IP et IHC (fp). Il convient pour détecter Cyclin C dans des échantillons de Humain.

Aperçu rapide pour Cyclin C anticorps (AA 233-283) (ABIN7453580)

Antigène: Cyclin C (CCNC)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cyclin C est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Cyclin C anticorps

Épitope: AA 233-283

Fonction: Rabbit anti-Cyclin C Antibody, Affinity Purified

Homologie: Mouse,Rat,Chicken,Bovine

Purification: Affinity Purified

Immunogène: between AA 233 and 283

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Cyclin C

Antigène: Cyclin C (CCNC)

Autre désignation: Cyclin C

Sujet: Background: Cyclin C is a member of the cyclin family of regulatory proteins that associate with and activate cyclin-dependent kinases (CDKs) to regulate cell cycle progression. Cyclins exhibit periodicity in their expression and activity which is regulated transcriptionally and post-transcriptionally via phosphorylation and ubiquitination. Cyclin C associates with cyclin-dependent kinase 8 (CDK8). It is also a component of the Mediator complex, a coactivator complex that provides a scaffold to link gene-specific transcription factors to RNA polymerase II and the general transcription machinery.

ID gène: 892

NCBI Accession: NP_005181

UniProt: P24863

Pathways: Cycle Cellulaire, Regulation of Lipid Metabolism by PPARalpha