RNF40 anticorps (AA 540-590)
-
- Antigène Voir toutes RNF40 Anticorps
- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
-
Épitope
- AA 540-590
-
Reactivité
- Humain
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp RNF40 est non-conjugé
-
Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- Fonction
- Rabbit anti-RNF40 Antibody, Affinity Purified
- Purification
- Affinity Purified
- Immunogène
- between AA 540 and 590
- Isotype
- IgG
- Top Product
- Discover our top product RNF40 Anticorps primaire
-
-
- Indications d'application
-
IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- Restrictions
- For Research Use only
-
- Concentration
- 200 μg/mL
- Buffer
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Date de péremption
- 12 months
-
- Antigène
- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
- Autre désignation
- RNF40 (RNF40 Produits)
- Synonymes
- anticorps AI848422, anticorps mKIAA0661, anticorps BRE1B, anticorps RBP95, anticorps STARING, anticorps ring finger protein 40, anticorps RNF40, anticorps Rnf40
- Sujet
- Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes and the ligation of ubiquitin to the target protein by E3 enzymes. Ring finger protein 40 (RNF40) is a member of the RING type E3 ubiquitin ligases. RNF40 forms a complex with RNF20 to carry out H2B monoubiquitination in association with hPAF and the UbcH6 ubiquitin E2-conjugating enzyme. H2B monoubiquitination by RN40/RNF20 has been shown to be associated with increased H3 methylation and gene transcription.
- ID gène
- 9810
- NCBI Accession
- NP_055586
- UniProt
- O75150
-