Paxillin anticorps (AA 1-50)

N° du produit ABIN7453855

Cet anticorps Lapin Polyclonal détecte spécifiquement Paxillin dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour Paxillin anticorps (AA 1-50) (ABIN7453855)

Antigène: Paxillin (PXN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Paxillin est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-Paxillin anticorps

Épitope: AA 1-50

Fonction: Rabbit anti-Paxillin Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 1 and 50

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:100 - 1:500. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.

IP: 1 - 5 μg/mg lysate

WB: 1:5,000 - 1:20,000

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur Paxillin

Antigène: Paxillin (PXN)

Autre désignation: Paxillin

Sujet: Background: Paxillin functions as a signal transduction adaptor protein that localizes to focal adhesions and is involved in cell-adhesion and motility. Paxillin is a substrate of several protein kinases such as Src, FAK, and JNK. Serine and threonine phosphorylation of Paxillin appears to dictate its specific cellular activities.

ID gène: 5829

NCBI Accession: NP_001074324

UniProt: P49023

Pathways: Signalisation MAPK, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling