GTF3C2 anticorps (AA 75-125)

N° du produit ABIN7454394

Détail du produit anti-GTF3C2 anticorps

Antigène: GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))

Épitope: AA 75-125

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GTF3C2 est non-conjugé

Application: Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Fonction: Rabbit anti-GTF3C2/TFIIIC110 Antibody, Affinity Purified

Homologie: Orangutan

Purification: Affinity Purified

Immunogène: between AA 75 and 125

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 5 μg/mg lysate

WB: Not recommended.

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur GTF3C2

Antigène: GTF3C2 (General Transcription Factor IIIC, Polypeptide 2, beta 110kDa (GTF3C2))

Autre désignation: GTF3C2/TFIIIC110 (GTF3C2 Produits)

Synonymes: anticorps TFIIIC110, anticorps GTF3C2, anticorps MGC155253, anticorps TF3C-beta, anticorps DKFZp469M0113, anticorps 1300004C11Rik, anticorps 2610510G03Rik, anticorps AI225816, anticorps AU041069, anticorps mKIAA0011, anticorps TFIIIC-BETA, anticorps general transcription factor IIIC subunit 2, anticorps general transcription factor IIIC, polypeptide 2, beta, anticorps Gtf3c2, anticorps GTF3C2

Sujet: Background: General transcription factor 3C polypeptide 2 (GTF3C2/TFIIIC110) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. The functional contribution of GTF3C2/TFIIIC110 to the TFIIIC complex has not been fully determined. TFIIIC that is not associated with GTF3C2/TFIIIC110 has been purified, and it has been proposed that GTF3C2/TFIIIC110 functions to activate the TFIIIC complex for RNA polymerase III transcription. Recent studies argue against this model of GTF3C2/TFIIIC110 function.

ID gène: 2976

NCBI Accession: NP_001512

UniProt: Q8WUA4