Bcl-2 anticorps (AA 50-100)
Aperçu rapide pour Bcl-2 anticorps (AA 50-100) (ABIN7454495)
Antigène
Voir toutes Bcl-2 (BCL2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- AA 50-100
-
Fonction
- Rabbit anti-Bcl-2 Antibody, Affinity Purified
-
Purification
- Affinity Purified
-
Immunogène
- Between AA 50 and 100
-
Isotype
- IgG
-
-
-
-
Indications d'application
-
IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended. A303-675A has not performed satisfactorily when used for WB of Bcl-2 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of Bcl-2.
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1000 μg/mL
-
Buffer
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Date de péremption
- 12 months
-
-
- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
-
Autre désignation
- Bcl-2
-
Sujet
- Background: B-cell CLL/lymphoma 2 (Bcl-2) is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of Bcl-2, such as in the case of translocation of Bcl-2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma [taken from NCBI Entrez Gene (Gene ID: 596)].
-
ID gène
- 596
-
NCBI Accession
- NP_000624
-
UniProt
- P10415
-
Pathways
- Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Antigène
-