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MDC1 anticorps (AA 925-975)

Cet anticorps Lapin Polyclonal détecte spécifiquement MDC1 dans WB, IP et IHC (fp). Il présente une réactivité envers Humain.

N° du produit ABIN7454586

Aperçu rapide pour MDC1 anticorps (AA 925-975) (ABIN7454586)

Antigène

Voir toutes MDC1 Anticorps

MDC1 (Mdc1 (MDC1))

Reactivité

58
45
16
12
11
2
1
1

Humain

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

28
6
6
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

Cet anticorp MDC1 est non-conjugé

Application

57
23
13
13
13
13
12
10
9
5
3
1
1
1
1

Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Discover our top product MDC1 Anticorps primaire

Épitope
21

15

10

9

5

3

2

1

1

1

1

1

1

1

1

1

1

1
AA 925-975

Fonction

Rabbit anti-MDC1 Antibody, Affinity Purified

Purification

Affinity Purified

Immunogène

between AA 925 and 975

Isotype

IgG
anti-Mdc1 (MDC1) (AA 1-100) antibody
MDC1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Mdc1 (MDC1) antibody
MDC1 Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 31-130) antibody
MDC1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 1-350) antibody
MDC1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody (HRP)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 HRP

anti-Mdc1 (MDC1) (N-Term) antibody (FITC)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 FITC

anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 Biotin

anti-Mdc1 (MDC1) (N-Term) antibody (PE)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 PE

anti-Mdc1 (MDC1) (N-Term) antibody (APC)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 APC

Indications d'application

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 4 μg/mg lysate
WB: 1:1,000 - 1:10,000

Restrictions

For Research Use only
Concentration

1000 μg/mL

Buffer

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

4 °C

Date de péremption

12 months
Antigène

MDC1 (Mdc1 (MDC1))

Autre désignation

MDC1

Sujet

Background: Mediator of DNA damage checkpoint protein 1 (Mdc1) is required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. It may serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. It is also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis [taken from the Universal Protein Resource (UniProt) Q5PSV9].

ID gène

9656

NCBI Accession

NP_055456

UniProt

Q14676

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