NCOA2 anticorps (C-Term)

N° du produit ABIN7454615

Cet anticorps anti-NCOA2 est un anticorps Lapin Polyclonal détectant NCOA2 dans WB, IP et IHC (fp). Adapté pour Humain et Souris.

Aperçu rapide pour NCOA2 anticorps (C-Term) (ABIN7454615)

Antigène: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Détail du produit anti-NCOA2 anticorps

Épitope: C-Term

Fonction: Rabbit anti-NCOA2/SRC2 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogène: between AA 1400 and C-term

Isotype: IgG

Information d'application

Indications d'application:

IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 1 - 4 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Stockage

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur NCOA2

Antigène: NCOA2 (Nuclear Receptor Coactivator 2 (NCOA2))

Autre désignation: NCOA2/SRC2

Sujet: Background: Nuclear Receptor Coactivator 2 (NCOA2) is a member of the p160 family of nuclear receptor coactivators that also includes steroid receptor coactivator-1 (SRC-1) and p300/CBP-interacting protein (p/CIP). As Coactivators, this group of proteins helps recruit acetyltransferases and methyltransferases such as p300/CBP and CARM1 to facilitate chromatin remodeling and transcription factor recruitment, and to enhance gene expression. NCOA2 has been demonstrated to be important for the control of energy balance between white and brown adipose tissue.

ID gène: 10499

NCBI Accession: NP_006531

UniProt: Q15596

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling