Recombinant CD247 anticorps (C-Term)

N° du produit ABIN7455240

Cet anticorps Lapin Monoclonal détecte spécifiquement CD247 dans WB, IP, IF (p) et IHC (fp). Il présente une réactivité envers Humain.

Aperçu rapide pour Recombinant CD247 anticorps (C-Term) (ABIN7455240)

Antigène: CD247 (CD247 Molecule (CD247))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CD247 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: BL-336-1B2

Détail du produit anti-CD247 anticorps

Épitope: C-Term

Fonction: Rabbit anti-CD247/CD3Z Recombinant Monoclonal Antibody [BL-336-1B2]

Homologie: Mouse,Sheep,Pig

Immunogène: between AA 150 to 164 (C-term)

Isotype: IgG

Information d'application

Indications d'application:

IHC-IF: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 20 μL/mg lysate

WB: 17:40:00

Restrictions: For Research Use only

Stockage

Concentration: 100 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Date de péremption: 12 months

Détails sur CD247

Antigène: CD247 (CD247 Molecule (CD247))

Autre désignation: CD247/CD3Z

Sujet: Background: T-cell surface glycoprotein CD3 zeta chain is encoded by the gene CD247, also known as CD3Z or CD3 zeta. CD247/CD3 zeta, together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response [taken from NCBI Entrez Gene (Gene ID: 919)].

ID gène: 919

NCBI Accession: NP_932170

UniProt: P20963

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway