KLRG1 anticorps (FITC)

N° du produit ABIN7456922

Détail du produit anti-KLRG1 anticorps (FITC)

Antigène: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Reactivité: Humain

Hôte: Golden Syrian Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp KLRG1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: 2F1

Isotype: IgG

Information d'application

Indications d'application: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Commentaires:

Matching Isotype Control: FITC Syrian Hamster IgG Isotype Control (ABIN7469730)

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur KLRG1

Antigène: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Autre désignation: KLRG-1 (KLRG1 Produits)

Synonymes: anticorps KLRG1, anticorps 2F1-Ag, anticorps MAFA, anticorps MAFA-L, anticorps 2F1, anticorps CLEC15A, anticorps MAFA-2F1, anticorps MAFA-LIKE, anticorps killer cell lectin like receptor G1, anticorps killer cell lectin-like receptor subfamily G, member 1, anticorps KLRG1, anticorps Klrg1

Sujet: MAFA, 2F20-Ag,Killer cell lectin-like receptor G1 (KLRG1) is the mouse homolog of the rat mast cell function-associated antigen (MAFA or 2F1-Ag).  KLRG1 is a type II membrane glycoprotein that was first identified on the surface of rat mast cell line RBL-2H3.  It is composed of a homodimer of glycosylated 30-38 kD subunits.  Mouse and human homologs of KLRG1 are expressed by subsets of NK cells and lymphokine-activated killer (LAK) cells but not mast cells.  KLRG1 is also expressed on subsets of CD8+ and CD4+ cells, including CD4+ and CD8+ effector/memory cells, potent regulatory CD4+ T cells.  KLRG1 may be involved in regulating NK cell homeostasis.  KLRG20 was found to recognize cadherins and thus inhibit immune responses by regulating the effector function and the developmental processes of NK and T cells.

ID gène: 10219, 50928

UniProt: Q96E93, O88713