CD28 anticorps
Aperçu rapide pour CD28 anticorps (ABIN7457969)
Antigène
Voir toutes CD28 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Purification
- Purified
-
Stérilité
- 0.2 μm filtered
-
niveau d'endotoxine
- Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
-
Isotype
- IgG1, kappa
-
-
anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reactivité: Humain, Souris, Rat FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Hôte: Lapin Polyclonal unconjugated
anti-CD28 (CD28) antibodyCD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, ICC, IHC (fro) Hôte: Souris Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) antibody (FITC)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 FITC
anti-CD28 (CD28) antibodyCD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, Func, ICC, IHC (fro) Hôte: Souris Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) (AA 19-152) antibodyCD28 Reactivité: Humain FACS, ELISA Hôte: Lapin Monoclonal DM61 unconjugated Recombinant Antibody
anti-CD28 (CD28) antibodyCD28 Reactivité: Rat FACS, IP Hôte: Souris Monoclonal JJ319 unconjugated
anti-CD28 (CD28) antibody (PE)CD28 Reactivité: Rat FACS Hôte: Souris Monoclonal JJ319 PE
anti-CD28 (CD28) antibody (PerCP)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PerCP
anti-CD28 (CD28) antibody (PE)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PE
anti-CD28 (CD28) antibody (APC)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 APC
-
-
Indications d'application
- Optimal working dilution should be determined by the investigator.
-
Commentaires
-
Matching Isotype Control: AF/LE Purified Mouse IgG1, κ Isotype Control (ABIN7469767)
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.5 mg/mL
-
Buffer
- PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)
-
Agent conservateur
- Azide free
-
Stock
- 4 °C
-
Stockage commentaire
- Store at 2~8°C. Do not freeze.
-
-
- CD28
-
Autre désignation
- CD28
-
Sujet
- PAS2,MNS,HGpMiX,GYPA,GPSAT,CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
-
ID gène
- 940
-
UniProt
- P10747
-
Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Antigène
-
