CD28 anticorps
Aperçu rapide pour CD28 anticorps (ABIN7457969)
Antigène
Voir toutes CD28 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Purified
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Stérilité
- 0.2 μm filtered
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niveau d'endotoxine
- Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
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Isotype
- IgG1, kappa
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anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reactivité: Humain, Souris, Rat FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Hôte: Lapin Polyclonal unconjugated
anti-CD28 (CD28) antibodyCD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Hôte: Souris Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) antibody (FITC)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 FITC
anti-CD28 (CD28) antibodyCD28 Reactivité: Humain, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Hôte: Souris Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) (AA 19-152) antibodyCD28 Reactivité: Humain FACS, ELISA Hôte: Lapin Monoclonal DM61 unconjugated Recombinant Antibody
anti-CD28 (CD28) antibodyCD28 Reactivité: Rat FACS, IP Hôte: Souris Monoclonal JJ319 unconjugated
anti-CD28 (CD28) antibody (PE)CD28 Reactivité: Rat FACS Hôte: Souris Monoclonal JJ319 PE
anti-CD28 (CD28) antibody (PerCP)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PerCP
anti-CD28 (CD28) antibody (PE)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 PE
anti-CD28 (CD28) antibody (APC)CD28 Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal CD28-2 APC
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Matching Isotype Control: AF/LE Purified Mouse IgG1, κ Isotype Control (ABIN7469767)
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)
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Agent conservateur
- Azide free
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Stock
- 4 °C
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Stockage commentaire
- Store at 2~8°C. Do not freeze.
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- CD28
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Autre désignation
- CD28
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Sujet
- PAS2,MNS,HGpMiX,GYPA,GPSAT,CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
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ID gène
- 940
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UniProt
- P10747
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Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
Antigène
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