E2F5 anticorps

N° du produit ABIN7464416

Détail du produit anti-E2F5 anticorps

Antigène: E2F5

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp E2F5 est non-conjugé

Application: Western Blotting (WB)

Specificité: Knockdown/Knockout validation was supported by references (PMID:36883841)

Réactivité croisée: Humain, Souris

Purification: Purified by antigen-affinity chromatography.

Classe de qualité: KO Validated

Immunogène: Recombinant protein encompassing a sequence within the center region of human E2F5. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:20000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HA-human E2F5-transfected 293T cells , A549 , H1299 , HCT116 , mouse placenta , mouse leukocyte treated with CFA

Validation: KO/KD, Orthogonal, Overexpression

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur E2F5

Antigène: E2F5

Autre désignation: E2F transcription factor 5 (E2F5 Produits)

Synonymes: anticorps AU024671, anticorps E2F-5, anticorps E2f-5, anticorps E2F4, anticorps cb735, anticorps zgc:111879, anticorps E2F transcription factor 5, anticorps E2f5, anticorps e2f5, anticorps E2F5

Sujet: E2F transcription factor 5 , E2F-5,The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionarily conserved domains that are present in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein is differentially phosphorylated and is expressed in a wide variety of human tissues. It has higher identity to E2F4 than to other family members. Both this protein and E2F4 interact with tumor suppressor proteins p130 and p107, but not with pRB. Alternative splicing results in multiple variants encoding different isoforms. [provided by RefSeq]

Poids moléculaire: 38 kDa

ID gène: 1875

UniProt: Q15329