Bcl-2 anticorps (pSer87)
Aperçu rapide pour Bcl-2 anticorps (pSer87) (ABIN7464672)
Antigène
Voir toutes Bcl-2 (BCL2) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer87
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Réactivité croisée
- Humain
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Carrier-protein conjugated synthetic peptide surrounding phospho Ser87 of human Bcl-2. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: Jurkat (1 μM paclitaxel treatment for 16 hr)
Validation: Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 2.06 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Autre désignation
- BCL2 apoptosis regulator
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Sujet
- BCL2 apoptosis regulator , Bcl-2 , PPP1R50,This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq]
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Poids moléculaire
- 26 kDa
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ID gène
- 596
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UniProt
- P10415
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Pathways
- Signalisation MAPK, Signalisation PI3K-Akt, Apoptose, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Antigène
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