TYK2 anticorps (N-Term)

N° du produit ABIN7467673

L’anticorps Lapin Polyclonal anti-TYK2 a été validé pour IF et ICC. Il convient pour détecter TYK2 dans des échantillons de Humain.

Aperçu rapide pour TYK2 anticorps (N-Term) (ABIN7467673)

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYK2 est non-conjugé

Application: Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-TYK2 anticorps

Épitope: N-Term

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the N-terminus region of human TYK2. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur TYK2

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Autre désignation: tyrosine kinase 2

Sujet: Tyrosine kinase 2 , IMD35 , JTK1,This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq]

Poids moléculaire: 134 kDa

ID gène: 7297

UniProt: P29597

Pathways: Signalistation JAK/STAT, Hepatitis C