ATP2B1 anticorps

N° du produit ABIN7468010

Détail du produit anti-ATP2B1 anticorps

Antigène: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP2B1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human PMCA1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HeLa Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur ATP2B1

Antigène: ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))

Autre désignation: ATPase plasma membrane Ca2+ transporting 1 (ATP2B1 Produits)

Synonymes: anticorps PMCA1, anticorps PMCA1kb, anticorps PMCA, anticorps 2810442I22Rik, anticorps E130111D10Rik, anticorps Pmca1, anticorps ATP2B1, anticorps DKFZp459A1127, anticorps atp2b1, anticorps Pmca1a, anticorps Pmca1b, anticorps Pmca1c, anticorps pmca1, anticorps pmca1a, anticorps sb:cb801, anticorps si:dkey-18o7.1, anticorps wu:fe47b06, anticorps wu:fi41d01, anticorps atp2b1b, anticorps ATPase plasma membrane Ca2+ transporting 1, anticorps ATPase, Ca++ transporting, plasma membrane 1, anticorps plasma membrane calcium-transporting ATPase 2, anticorps ATPase, Ca++ transporting, plasma membrane 1a, anticorps ATPase, Ca++ transporting, plasma membrane 1 L homeolog, anticorps ATP2B1, anticorps Atp2b1, anticorps atp2b1, anticorps LOC100180580, anticorps atp2b1a, anticorps atp2b1.L

Sujet:

Synonyms: ATPase plasma membrane Ca2+ transporting 1 , PMCA1 , PMCA1kb

Background: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Poids moléculaire: 139 kDa

ID gène: 490

UniProt: P20020

Pathways: Ribonucleoside Biosynthetic Process