ATP2B1 anticorps
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- Antigène Voir toutes ATP2B1 Anticorps
- ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ATP2B1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Réactivité croisée
- Humain, Souris, Rat
- Purification
- Purified by antigen-affinity chromatography.
- Immunogène
- Recombinant protein encompassing a sequence within the center region of human PMCA1. The exact sequence is proprietary.
- Isotype
- IgG
- Top Product
- Discover our top product ATP2B1 Anticorps primaire
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- Indications d'application
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Commentaires
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Positive Control: HeLa Validation: Orthogonal
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Antigène
- ATP2B1 (ATPase, Ca++ Transporting, Plasma Membrane 1 (ATP2B1))
- Autre désignation
- ATPase plasma membrane Ca2+ transporting 1 (ATP2B1 Produits)
- Synonymes
- anticorps PMCA1, anticorps PMCA1kb, anticorps PMCA, anticorps 2810442I22Rik, anticorps E130111D10Rik, anticorps Pmca1, anticorps ATP2B1, anticorps DKFZp459A1127, anticorps atp2b1, anticorps Pmca1a, anticorps Pmca1b, anticorps Pmca1c, anticorps pmca1, anticorps pmca1a, anticorps sb:cb801, anticorps si:dkey-18o7.1, anticorps wu:fe47b06, anticorps wu:fi41d01, anticorps atp2b1b, anticorps ATPase plasma membrane Ca2+ transporting 1, anticorps ATPase, Ca++ transporting, plasma membrane 1, anticorps plasma membrane calcium-transporting ATPase 2, anticorps ATPase, Ca++ transporting, plasma membrane 1a, anticorps ATPase, Ca++ transporting, plasma membrane 1 L homeolog, anticorps ATP2B1, anticorps Atp2b1, anticorps atp2b1, anticorps LOC100180580, anticorps atp2b1a, anticorps atp2b1.L
- Sujet
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Synonyms: ATPase plasma membrane Ca2+ transporting 1 , PMCA1 , PMCA1kb
Background: The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
- Poids moléculaire
- 139 kDa
- ID gène
- 490
- UniProt
- P20020
- Pathways
- Ribonucleoside Biosynthetic Process
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