XPC anticorps

N° du produit ABIN7469198

Cet anticorps anti-XPC est un anticorps Souris Monoclonal détectant XPC dans WB, ICC, IHC (p) et IF. Adapté pour Humain.

Aperçu rapide pour XPC anticorps (ABIN7469198)

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp XPC est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: 3-26

Détail du produit anti-XPC anticorps

Réactivité croisée: Humain, Souris

Purification: Protein G purified

Immunogène: Recombinant XPC purified from E. coli

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HeLa whole cell extract

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.15 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur XPC

Antigène: XPC (Xeroderma Pigmentosum, Complementation Group C (XPC))

Autre désignation: XPC complex subunit, DNA damage recognition and repair factor

Sujet:

Synonyms: XPC complex subunit, DNA damage recognition and repair factor , RAD4 , XP3 , XPCC , p125

Background: The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]

Poids moléculaire: 106 kDa

ID gène: 7508

UniProt: Q01831

Pathways: Signalisation p53, Réparation de l'ADN