CLEC4D anticorps (APC)

N° du produit ABIN7505925

Détail du produit anti-CLEC4D anticorps (APC)

Antigène: CLEC4D (C-Type Lectin Domain Family 4, Member D (CLEC4D))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CLEC4D est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Fonction: Anti-Hu CD368 APC

Specificité: The mouse monoclonal antibody 9B9 recognizes an extracellular epitope of CD368, a type II transmembrane protein of C lectin family, expressed mainly on monocytes and neutrophils.

Purification: Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: CD368 ectodomain fused with human Fc

Clone: 9B9

Isotype: IgG2b kappa

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur CLEC4D

Antigène: CLEC4D (C-Type Lectin Domain Family 4, Member D (CLEC4D))

Autre désignation: CD368 (CLEC4D Produits)

Synonymes: anticorps CLEC4D, anticorps CLEC-6, anticorps CLEC6, anticorps CLECSF8, anticorps MCL, anticorps MPCL, anticorps Clecsf8, anticorps Mpcl, anticorps mcl, anticorps Mcl, anticorps C-type lectin domain family 4 member D, anticorps C-type lectin domain family 4, member d, anticorps C-type lectin domain family 4, member D, anticorps CLEC4D, anticorps LOC611536, anticorps Clec4d

Sujet: C-type lectin domain family 4 member D,CD368 is an approximately 25-30 kDa C-type lectin, which serves as one of pattern recognition receptors of the innate immune system. It recognizes pathogen-associated molecular patterns of bacteria and fungi, such as alpha-mannans or trehalose 6,6´-dimycolate, and transfers the signal downstream using associated Fc receptor gamma chain. CD368 is expressed on neutrophils, monocytes, and on some populations of blood dendritic cells, but it decreases during differentiation of monocytes into dendritic cells or macrophages. Increased expression can be induced by IFN-gamma, TNF-alpha, IL-6, and IL-10. CD368 triggering leads to driving of antigen-presenting cells maturation and to promotion of T cell differentiation into Th1 and Th17.,CLEC6, CLEC4D, dectin 3, MCL, MPCL

ID gène: 338339

UniProt: Q8WXI8