The mouse monoclonal antibody AYP1 recognizes an epitope within the extracellular part of CLEC2, a transmembrane glycoprotein expressed on activated plateles and on platelet microparticles.
Purification
Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
Immunogène
A recombinant extracellular domain of human CLEC2 (amino acids 68-229)
Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
anticorps 1810061I13Rik, anticorps CLEC2, anticorps CLEC2B, anticorps PRO1384, anticorps QDED721, anticorps Clec-2, anticorps Clec2, anticorps CLEC1B, anticorps RGD1563517, anticorps CLEC9A, anticorps C-type lectin domain family 1 member B, anticorps C-type lectin domain family 1, member b, anticorps C-type lectin domain family 1, member B, anticorps CLEC1B, anticorps Clec1b
Classe de substances
Viral Protein
Sujet
C-type lectin domain family 1 member B,CLEC2 (C-type lectin-like receptor 2) functions as a platelet receptor for the lymphatic endothelial marker, PDPN, and mediates platelet activation. Besides platelets, it can be found on myeloid cells and NK cells. CLEC2 functions also as an attachment factor for HIV-1 and facilitates its capture by platelets. Platelet-aggregating snake venom protein rhodocytin also binds to CLEC2.,CLEC1B, CLEC2B, PRO1384, QDED721