CLEC4A anticorps

N° du produit ABIN7506129

Détail du produit anti-CLEC4A anticorps

Antigène: CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CLEC4A est non-conjugé

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Fonction: Anti-Hu CD367 Purified

Specificité: The mouse monoclonal antibody 9E8 recognizes an extracellular epitope of human CD367, a type II transmembrane protein of C-lectin family, expressed mainly on antigen presenting cells.

Purification: Purified by protein-A affinity chromatography.

Immunogène: CD367 ectodomain fused with human Fc

Clone: 9E8

Isotype: IgG1 kappa

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-4 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur CLEC4A

Antigène: CLEC4A (C-Type Lectin Domain Family 4, Member A (CLEC4A))

Autre désignation: CD367 (CLEC4A Produits)

Synonymes: anticorps CLEC4A, anticorps CLECSF6, anticorps DCIR, anticorps DDB27, anticorps LLIR, anticorps Clecsf6, anticorps Dcir1, anticorps Clec4a, anticorps zinc finger protein 705A, anticorps C-type lectin domain family 4 member A, anticorps C-type lectin domain family 4, member A, anticorps C-type lectin domain family 4, member a2, anticorps ZNF705A, anticorps CLEC4A, anticorps Clec4a, anticorps Clec4a2

Sujet: C-type lectin domain family 4 member A,CD367 is an approximately 20-28 kDa C-type lectin with immunoreceptor tyrosine-based inhibitory motif (ITIM) in its cytoplasmic part. CD367 binds in calcium-dependent manner to mannose, fucose, and weakly also to N-acetylglucosamine. It is expressed on dendritic cells, macrophages, monocytes, B cells, and neutrophils. In rheumatoid arthitis patients CD367 is expressed also on CD4+ T cells. After ligand-mediated triggering, it is internalized by clathrin-dependent endocytosis and contributes to the antigen presentation to CD8+ T cells. It may also be involved in modulation of the antigen presenting cell response.,DCIR, CLEC4A, LLIR

ID gène: 50856

UniProt: Q9UMR7