Insulin Receptor anticorps

N° du produit ABIN7538096

Cet anticorps Lapin Polyclonal détecte spécifiquement Insulin Receptor dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Insulin Receptor anticorps (ABIN7538096)

Antigène: Insulin Receptor (INSR)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Insulin Receptor est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-Insulin Receptor anticorps

Fonction: Rabbit polyclonal antibodies to Insulin Receptor

Specificité: Insulin receptor

Réactivité croisée (Details): May cross-react with other species

Purification: Immunogen affinity column

Immunogène: Peptide conjugated to KLH (GGKKNGRILTLPRSNPS)

Isotype: IgG, IgM

Information d'application

Indications d'application: Western blot: 0.1-1.0 μg/mL

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Glycine pH 7.2

Stock: 4 °C,-80 °C

Stockage commentaire: Short term up to 1 month at 2-8°C, long term can be held for up to five years at -70°C

Détails sur Insulin Receptor

Antigène: Insulin Receptor (INSR)

Autre désignation: insulin receptor

Sujet: INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.

Poids moléculaire: 42226 Da

ID gène: 3643

NCBI Accession: NP_000199

UniProt: P06213

Pathways: Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity