TRAIL anticorps

N° du produit ABIN7539279

Cet anticorps Lapin Polyclonal détecte spécifiquement TRAIL dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour TRAIL anticorps (ABIN7539279)

Antigène: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TRAIL est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-TRAIL anticorps

Fonction: Rabbit Anti-Human TRAIL/Apo2L Polyclonal Antibody

Specificité: Chromosomal location:3q26

Purification: Protein-A purified

Immunogène: recombinant human TRAIL/ApoL2

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized antibody is stable for at least 2 years at -20°C. After sterile reconstitution the antibody is stable at 2-8°C for up to 6 months. Frozen aliquots are stable for at least 6 months when stored at -20°C. Addition of a carrier protein or 50% glycerol is recommended for frozen aliquots.

Date de péremption: 24 months

Détails sur TRAIL

Antigène: TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))

Autre désignation: TRAIL/Apo2L

Sujet:

Synonyms: TNFSF10, TL2, APO2L, CD253, TRAIL, Apo-2L

Description: TNF-related apoptosis-inducing ligand (TRAIL) is a ligand molecule which induces apoptosis. It is a type II transmembrane protein with homology to other members of the tumor necrosis factor family. In humans, the gene that encodes for TRAIL is located at chromosome 3q26. TRAIL binds to the death receptors, DR4 and DR5. The process of apoptosis is caspase-8-dependent. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues.

ID gène: 8743

NCBI Accession: NM_003810, NP_003801

UniProt: P50591

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity