FGFR3 anticorps

N° du produit ABIN7539297

Cet anticorps Escherichia coli (E. coli) Monoclonal détecte spécifiquement FGFR3 dans Neut. Il présente une réactivité envers Humain.

Aperçu rapide pour FGFR3 anticorps (ABIN7539297)

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Fragment: Fab fragment

Reactivité: Humain

Hôte: Escherichia coli (E. coli)

Clonalité: Monoclonal

Conjugué: Cet anticorp FGFR3 est non-conjugé

Application: Neutralization (Neut)

Détail du produit anti-FGFR3 anticorps

Fonction: FGFR-3 neutralizing antibody antibody

Specificité: Chromosomal location:4p16.3

Purification: Ion exchange chromatography

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS

Stock: 4 °C,-20 °C

Stockage commentaire: Lyophilized samples are stable for up to a year at -20°C. Upon reconstitution, the Fab is stable for up to 1 month at 4°C or up to 1 year at -20°C.

Date de péremption: 24 months

Détails sur FGFR3

Antigène: FGFR3 (Fibroblast Growth Factor Receptor 3 (FGFR3))

Autre désignation: FGFR-3

Sujet: FGFR3, ACH, CEK2, JTK4, CD333, HSFGFR3EX,Fibroblast Growth Factor Receptor 3 (FGF R3) is a type I transmembrane tyrosine kinase receptor that binds FGF ligands along with heparin or heparin sulfateproteoglycans as cofactors. A segment of the membrane proximal Ig-like domain can be encoded by two different exons resulting in (IIIb) or (IIIc) isoforms. The IIIb or IIIc isoforms recognize FGF1, 2, 4, 8b, 8e, 8f, 9, and 17b. FGF R3 plays a role in skeletal, brain, lung, intestine, kidney, and skin development.

ID gène: 2261

NCBI Accession: NM_000142, NP_000133

UniProt: P22607

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Growth Factor Binding