DDIT3 anticorps (AA 87-192)

N° du produit ABIN7539832

L’anticorps Souris Monoclonal anti-DDIT3 a été validé pour IHC, ELISA, FACS et ICC. Il convient pour détecter DDIT3 dans des échantillons de Humain.

Aperçu rapide pour DDIT3 anticorps (AA 87-192) (ABIN7539832)

Antigène: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DDIT3 est non-conjugé

Application: Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 4E8E9

Détail du produit anti-DDIT3 anticorps

Épitope: AA 87-192

Fonction: DDIT3 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DDIT3 (AA: 87-192) expressed in E. Coli.

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur DDIT3

Antigène: DDIT3 (DNA-Damage-Inducible Transcript 3 (DDIT3))

Autre désignation: DDIT3

Sujet: This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members, such as C/EBP and LAP (liver activator protein), and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis, is activated by endoplasmic reticulum stress, and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified.

Poids moléculaire: 19.2 kDa

ID gène: 1649

UniProt: P35638

Pathways: Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Skeletal Muscle Fiber Development, Cell RedoxHomeostasis