Caspase 12 anticorps (Internal Region)

N° du produit ABIN7540612

N° du produit (Fournisseur): 600-401-mj3s

Cet anticorps anti-Caspase 12 est un anticorps Lapin Polyclonal détectant Caspase 12 dans WB, ELISA, IF et FM. Adapté pour Souris.

Aperçu rapide pour Caspase 12 anticorps (Internal Region) (ABIN7540612)

Antigène: Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Caspase 12 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Fluorescence Microscopy (FM)

Détail du produit anti-Caspase 12 anticorps

Épitope: Internal Region

N° du produit (Fournisseur): 600-401-mj3s

Fournisseur: Rockland

Fonction: Caspase 12 Antibody

Réactivité croisée (Details): This affinity purified antibody is directed against mouse Caspase 12.

Purification: The antibody was affinity purified from monospecific antiserum by immunoaffinity purification.

Stérilité: Sterile filtered

Immunogène: Anti-Caspase 12 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of mouse Caspase 12 conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000 - 1:50,000

IF_Microscopy_Dilution: 15 μg/mL

Western_Blot_Dilution: 5 μg/mL

Commentaires:

Anti-Caspase 12 Antibody has been tested in ELISA, IF, and WB.  Positive control used: NIH/3T3 and PC-12 lysates in Western Blot and NIH/3T3 in Immunofluorescence.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store vial at -20° C or below prior to opening. This vial contains a relatively low volume of reagent (25 μL). To minimize loss of volume dilute 1:10 by adding 225 μL of the buffer stated above directly to the vial. Recap, mix thoroughly and briefly centrifuge to collect the volume at the bottom of the vial. Use this intermediate dilution when calculating final dilutions as recommended below. Store the vial at -20°C or below after dilution. Avoid cycles of freezing and thawing.

Date de péremption: 12 months

Détails sur Caspase 12

Antigène: Caspase 12 (CASP12) (Caspase 12 (Gene/pseudogene) (CASP12))

Autre désignation: Casp12

Sujet: Rabbit Anti-Caspase 12 Antibody, Caspase 12 pseudogene 1, Casp12, Casp-12, CASP12P1,Casp12 (Caspase 12 (Gene/Pseudogene)) has no protease activity. It may reduce cytokine release in response to bacterial lipopolysaccharide during infections. Caspase 12 reduces activation of NF-kappa-B in response to TNF. Caspases (cysteinyl aspartate proteases) are involved in the signaling pathways of apoptosis, necrosis and inflammation. These enzymes can be divided into initiators and effectors. The initiator isoforms are activated by, and interact with, upstream adaptor molecules. Anti-Caspase 12 Antibody is useful for researchers interested in Amyotrophic lateral sclerosis (ALS), ATP synthesis, and Apoptosis research.

ID gène: 12364

NCBI Accession: NP_033938

UniProt: O08736

Pathways: Apoptose, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response