ARHGEF7 anticorps (AA 25-637)

N° du produit ABIN7600917

Cet anticorps Lapin Polyclonal détecte spécifiquement ARHGEF7 dans WB, ELISA, IHC, IF, ICC et FACS. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour ARHGEF7 anticorps (AA 25-637) (ABIN7600917)

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF7 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Détail du produit anti-ARHGEF7 anticorps

Épitope: AA 25-637

Fonction: Anti-ARHGEF7 Antibody Picoband®

Attributs du produit: Anti-ARHGEF7 Antibody Picoband® (ABIN7600917). Tested in WB, IHC, ICC/IF, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human ARHGEF7 recombinant protein (Position: S25-N637). Human ARHGEF7 shares 90.4% amino acid (aa) sequence identity with mouse ARHGEF7.

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bagrodia, S., Taylor, S. J., Jordon, K. A., Van Aelst, L., Cerione, R. A. A novel regulator of p21-activated kinases. J. Biol. Chem. 273: 23633-23636, 1998. 2. Feng, Q., Baird, D., Peng, X., Wang, J., Ly, T., Guan, J.-L., Cerione, R. A. Cool-1 functions as an essential regulatory node for EGF receptor- and Src-mediated cell growth. Nature Cell Biol. 8: 945-956, 2006. 3. Manser, E., Loo, T.-H., Koh, C.-G., Zhao, Z.-S., Chen, X.-Q., Tan, L., Tan, I., Leung, T., Lim, L. PAK kinases are ly coupled to the PIX family of nucleotide exchange factors. Molec. Cell 1: 183-192, 1998.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Détails sur ARHGEF7

Antigène: ARHGEF7 (rho Guanine Nucleotide Exchange Factor (GEF) 7 (ARHGEF7))

Autre désignation: ARHGEF7

Sujet: Rho guanine nucleotide exchange factor 7 is a protein that in humans is encoded by the ARHGEF7 gene. This gene encodes a protein that belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It forms a complex with the small GTP binding protein Rac1 and recruits Rac1 to membrane ruffles and to focal adhesions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.

Poids moléculaire: 80 kDa

ID gène: 8874

UniProt: Q14155

Pathways: EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation