Presenilin 1 anticorps (Catalytic Subunit)

N° du produit ABIN7602951

Cet anticorps Lapin Monoclonal détecte spécifiquement Presenilin 1 dans WB et FACS. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Presenilin 1 anticorps (Catalytic Subunit) (ABIN7602951)

Antigène: Presenilin 1 (PSEN1)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Presenilin 1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: AECD-16

Détail du produit anti-Presenilin 1 anticorps

Épitope: Catalytic Subunit

Fonction: Anti-Presenilin 1 Monoclonal Antibody

Attributs du produit: Anti-Presenilin 1 Monoclonal Antibody (ABIN7602951). Tested in WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Presenilin 1 Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein) . Requires the other members of the gamma-secretase complex to have a protease activity.

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-2000
IHC 1:50-200
FC 1:10

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: 0.5 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Détails sur Presenilin 1

Antigène: Presenilin 1 (PSEN1)

Autre désignation: PSEN1

Sujet:

Synonyms: Monocyte differentiation antigen CD14 ,Myeloid cell-specific leucine-rich glycoprotein,CD14,Monocyte differentiation antigen CD14, urinary form,Monocyte differentiation antigen CD14, membrane-bound form,CD14,

Tissue Specificity: Detected on macrophages (at protein level) (PubMed:1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes, also expressed by most tissue macrophages. .

Poids moléculaire: 25 kDa

UniProt: P49768

Pathways: Signalisation Notch, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport