Insulin Receptor anticorps

N° du produit ABIN7605279

Cet anticorps Lapin Monoclonal détecte spécifiquement Insulin Receptor dans WB, ICC et IF. Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour Insulin Receptor anticorps (ABIN7605279)

Antigène: Insulin Receptor (INSR)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp Insulin Receptor est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: GGA-9

Détail du produit anti-Insulin Receptor anticorps

Fonction: Anti-Insulin Receptor INSR Rabbit Monoclonal Antibody

Attributs du produit: Anti-Insulin Receptor INSR Rabbit Monoclonal Antibody (ABIN7605279). Tested in WB, ICC/IF applications. This antibody reacts with Human, Rat.

Purification: Affinity-chromatography

Immunogène: A synthesized peptide derived from human Insulin Receptor

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000
ICC/IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

Concentration: Lot specific

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Détails sur Insulin Receptor

Antigène: Insulin Receptor (INSR)

Autre désignation: INSR

Sujet:

Synonyms: Insulin receptor,IR,2.7.10.1,CD220,Insulin receptor subunit alpha,Insulin receptor subunit beta,INSR,

Tissue Specificity: Isoform Long and isoform Short are predominantly expressed in tissue targets of insulin metabolic effects: liver, adipose tissue and skeletal muscle but are also expressed in the peripheral nerve, kidney, pulmonary alveoli, pancreatic acini, placenta vascular endothelium, fibroblasts, monocytes, granulocytes, erythrocytes and skin. Isoform Short is preferentially expressed in fetal cells such as fetal fibroblasts, muscle, liver and kidney. Found as a hybrid receptor with IGF1R in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Overexpressed in several tumors, including breast, colon, lung, ovary, and thyroid carcinomas. .

Poids moléculaire: 73 kDa

UniProt: P06213

Pathways: Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity