SMURF2 anticorps
Aperçu rapide pour SMURF2 anticorps (ABIN7606330)
Antigène
Voir toutes SMURF2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-SMURF 2 Rabbit Monoclonal Antibody
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Attributs du produit
- Anti-SMURF 2 Rabbit Monoclonal Antibody (ABIN7606330). Tested in WB application. This antibody reacts with Human, Mouse, Rat.
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Purification
- Affinity-chromatography
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Immunogène
- A synthesized peptide derived from human SMURF 2 E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then ly transfers the ubiquitin to targeted substrates. Interacts with SMAD1 and SMAD7 in order to trigger their ubiquitination and proteasome-dependent degradation.
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Isotype
- IgG
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Indications d'application
- WB 1:500-1:1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Reconstitution
- Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL
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Concentration
- Lot specific
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Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol, 0.4-0.5 mg/mL BSA.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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- SMURF2 (SMAD Specific E3 Ubiquitin Protein Ligase 2 (SMURF2))
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Autre désignation
- SMURF2
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Sujet
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Synonyms: Neurogenic locus notch homolog protein 4,Notch 4,hNotch4,Notch 4 extracellular truncation,Notch 4 intracellular domain,NOTCH4,INT3,
Tissue Specificity: Highly expressed in the heart, moderately in the lung and placenta and at low levels in the liver, skeletal muscle, kidney, pancreas, spleen, lymph node, thymus, bone marrow and fetal liver. No expression was seen in adult brain or peripheral blood leukocytes.
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Poids moléculaire
- 41 kDa
Antigène
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