FOXO3 anticorps (AA 581-673)

N° du produit ABIN731168

1 publication est disponible pour ce produit. L’anticorps anti-FOXO3 Polyclonal produit chez le Lapin a été validé pour WB, ELISA, IHC (p) et IF (cc). Il convient pour la détection de FOXO3 dans des échantillons provenant de Humain, Souris et Rat. }

Aperçu rapide pour FOXO3 anticorps (AA 581-673) (ABIN731168)

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FOXO3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Détail du produit anti-FOXO3 anticorps

Épitope: AA 581-673

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human FOXO3A

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-FOXO3 (ABIN731168)

Morales, Abrigo, Acuña, Santos, Bader, Brandan, Simon, Olguin, Cabrera, Cabello-Verrugio: "Angiotensin-(1-7) attenuates disuse skeletal muscle atrophy in mice via its receptor, Mas." dans: Disease models & mechanisms, Vol. 9, Issue 4, pp. 441-9, (2016) (PubMed).

Détails sur FOXO3

Antigène: FOXO3 (Forkhead Box O3 (FOXO3))

Autre désignation: FOXO3A

Sujet:

Synonyms: FOXO2, AF6q21, FKHRL1, FOXO3A, FKHRL1P2, Forkhead box protein O3, AF6q21 protein, Forkhead in rhabdomyosarcoma-like 1, FOXO3

Background: Transcriptional activator which triggers apoptosis in the absence of survival factors, including neuronal cell death upon oxidative stress. Recognizes and binds to the DNA sequence 5'-[AG]TAAA[TC]A-3'. Participates in post-transcriptional regulation of MYC: following phosphorylation by MAPKAPK5, promotes induction of miR-34b and miR-34C expression, 2 post-transcriptional regulators of MYC that bind to the 3'UTR of MYC transcript and prevent its translation.

ID gène: 2309

UniProt: O43524

Pathways: Cycle Cellulaire, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis