STAT2 anticorps

N° du produit ABIN7659945

Cet anticorps anti-STAT2 Monoclonal Souris (Clone STAT2-2650) (ABIN7659945) détecte spécifiquement STAT2 dans IHC et IHC (fp). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour STAT2 anticorps (ABIN7659945)

Antigène: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp STAT2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: STAT2-2650

Détail du produit anti-STAT2 anticorps

Fonction: STAT2(STAT2/2650)

Attributs du produit: Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN- is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Immunogène: Recombinant full-length human STAT2 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Positive Control: Ramos and Jurkat cell lysates. HeLa cell extract. Human lung carcinoma tissue.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: PBS, 0.05 % BSA, 0.05 % azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire:

Stable at room temperature or 37°C for 7 days.

Store at 2 to 8°C. Protect fluorescent conjugates from light

Date de péremption: 24 months

Détails sur STAT2

Antigène: STAT2 (Signal Transducer and Activator of Transcription 2, 113kDa (STAT2))

Autre désignation: STAT2

Sujet:

Synonyms: Homo sapiens interferon alpha induced transcriptional activator, interferon alpha induced transcriptional activator (ISGF3), P113, signal transducer and activator of transcription 2 113kD (STAT113), Signal transducer and activator of transcription 2 (STAT2)

Gene Symbol: STAT2

Poids moléculaire: 113 kDa

ID gène: 6773

UniProt: P52630

Pathways: Signalistation JAK/STAT, Hepatitis C, CXCR4-mediated Signaling Events