FLT3 anticorps

N° du produit ABIN7670057

Cet anticorps anti-FLT3 est un anticorps Souris Monoclonal détectant FLT3 dans FACS. Adapté pour Humain.

Aperçu rapide pour FLT3 anticorps (ABIN7670057)

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FLT3 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: 4G8

Détail du produit anti-FLT3 anticorps

Fonction: Purified Anti-Human CD135 Antibody[4G8]

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: ≥ 1 mg/mL

Buffer: Phosphate buffered solution, pH 7.2, containing 0.05 % proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: avoid freeze / thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur FLT3

Antigène: FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

Autre désignation: CD135

Sujet: Fetal Liver Kinase,Fms-Like Tyrosine Kinase,Stem Cell Tyrosine Kinase,Receptor-Type Tyrosine-Protein Kinase FLT,FLT,FLK,STK,FLT3,CD135,FLK-2,FLK2,STK1,Fetal Liver Kinase-2,FL Cytokine Receptor,FLT-3,Fms-Like Tyrosine Kinase 3,Receptor-Type Tyrosine-Protein Kinase FLT3,Stem Cell Tyrosine Kinase 1,STK-1,Flt3/Flk2, STK-1,CD 135,CD135 antigen,Fetal liver kinase 2,Flk 2,Flt 3,FMS like tyrosine kinase 3,Fms related tyrosine kinase 3,Fms-Related Tyrosine Kinase 3,Growth factor receptor tyrosine kinase type III,Ly-72,OTTHUMP0000004234,Receptor type tyrosine protein kinase FLT3,Stk 1,Tyrosine protein kinase receptor FLT3,Tyrosine-protein kinase receptor FLT3,This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.

UniProt: P36888

Pathways: Signalisation RTK