PPARA anticorps (AA 1-250)

N° du produit ABIN7674426

L’anticorps Souris Monoclonal anti-PPARA a été validé pour WB et ELISA. Il convient pour détecter PPARA dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PPARA anticorps (AA 1-250) (ABIN7674426)

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPARA est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 11H4

Détail du produit anti-PPARA anticorps

Épitope: AA 1-250

Fonction: PPARA antibody

Purification: Protein A+G purification

Pureté: ≥95 % as determined by SDS-PAGE

Immunogène:

Immunogen sequence: 1-250aa

Immunogen: peroxisome proliferator-activated receptor alpha

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur PPARA

Antigène: PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Autre désignation: PPARA

Sujet:

Synonyms: Peroxisome proliferator-activated receptor alpha (PPAR-alpha)|Nuclear receptor subfamily 1 group C member 1|PPARA|NR1C1|PPAR

Background: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.

Poids moléculaire: 52-55 kDa

ID gène: 5465

UniProt: Q07869

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C