NADPH Oxidase 4 anticorps (AA 81-180)

N° du produit ABIN737526

Cet anticorps anti-NADPH Oxidase 4 est un anticorps Lapin Polyclonal détectant NADPH Oxidase 4 dans WB, ELISA, FACS, IP, ICC, IHC (p), IF (cc), IF (p) et IHC (fro). Adapté pour Humain, Rat et Souris. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour NADPH Oxidase 4 anticorps (AA 81-180) (ABIN737526)

Antigène: NADPH Oxidase 4 (NOX4)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NADPH Oxidase 4 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-NADPH Oxidase 4 anticorps

Épitope: AA 81-180

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from mouse Nox-4

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
IP(1-2 μg)
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-NADPH Oxidase 4 (ABIN737526)

Ulmasov, Bruno, Oshima, Cheng, Holly, Parise, Egan, Edwards: "CLIC1 null mice demonstrate a role for CLIC1 in macrophage superoxide production and tissue injury." dans: Physiological reports, Vol. 5, Issue 5, (2017) (PubMed).

Khan, Byer, Khan: "Exposure of Madin-Darby canine kidney (MDCK) cells to oxalate and calcium oxalate crystals activates nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase." dans: Urology, Vol. 83, Issue 2, pp. 510.e1-7, (2014) (PubMed).

Détails sur NADPH Oxidase 4

Antigène: NADPH Oxidase 4 (NOX4)

Autre désignation: NADPH oxidase 4

Sujet:

Synonyms: AI64821, NADPH oxidase 4, Kidney oxidase-1, KOX-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase, Superoxide-generating NADPH oxidase 4, Nox4, Renox

Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB.

ID gène: 50490

UniProt: Q9JHI8

Pathways: Carbohydrate Homeostasis, Smooth Muscle Cell Migration