SCARB1 anticorps (AA 21-100)

N° du produit ABIN738936

Cet anticorps anti-SCARB1 est un anticorps Lapin Polyclonal détectant SCARB1 dans WB, ELISA, FACS et IHC (p). Adapté pour Humain, Rat, Souris et Poulet. Ce Primary Antibody a été cité dans 2+ publications.

Aperçu rapide pour SCARB1 anticorps (AA 21-100) (ABIN738936)

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Reactivité: Humain, Rat, Souris, Poulet

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SCARB1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SCARB1 anticorps

Épitope: AA 21-100

Réactivité croisée: Poulet, Humain, Souris, Rat

Homologie: Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human CD36L1

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-SCARB1 (ABIN738936)

Gabriel, Becher-Deichsel, Hlavaty, Mair, Walter: "The physiological expression of scavenger receptor SR-B1 in canine endometrial and placental epithelial cells and its potential involvement in pathogenesis of pyometra." dans: Theriogenology, Vol. 85, Issue 9, pp. 1599-1609.e2, (2016) (PubMed).

Pollard, Blesso, Zabalawi, Fulp, Gerelus, Zhu, Lyons, Nuradin, Francone, Li, Sahoo, Thomas, Sorci-Thomas et al.: "Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester ..." dans: The Journal of biological chemistry, Vol. 290, Issue 25, pp. 15496-511, (2015) (PubMed).

Détails sur SCARB1

Antigène: SCARB1 (Scavenger Receptor Class B, Member 1 (SCARB1))

Autre désignation: Scavenger receptor class B member 1

Sujet:

Synonyms: CLA1, SRB1, CLA-1, SR-BI, CD36L1, HDLQTL6, Scavenger receptor class B member 1, CD36 and LIMPII analogous 1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, CD36, SCARB1

Background: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity. Receptor for hepatitis C virus glycoprotein E2. Binding between SCARB1 and E2 was found to be independent of the genotype of the viral isolate. Plays an important role in the uptake of HDL cholesteryl ester (By similarity).

ID gène: 949

UniProt: Q8WTV0

Pathways: Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Lipid Metabolism, SARS-CoV-2 Protein Interactome