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MDC1 anticorps (AA 31-130) (Cy7)

Cet anticorps anti-MDC1 est un anticorps Lapin Polyclonal détectant MDC1 dans WB, IF (cc) et IF (p). Adapté pour Humain, Souris et Rat.

N° du produit ABIN739746

Aperçu rapide pour MDC1 anticorps (AA 31-130) (Cy7) (ABIN739746)

Antigène

Voir toutes MDC1 Anticorps

MDC1 (Mdc1 (MDC1))

Reactivité

58
44
15
12
11
2
1
1

Humain, Souris, Rat

Hôte

Lapin

Clonalité

Polyclonal

Conjugué

29
6
6
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

Cet anticorp MDC1 est conjugé à/à la Cy7

Application

57
23
13
13
12
12
12
10
9
6
3
2
1
1
1

Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Discover our top product MDC1 Anticorps primaire

Épitope
21

14

10

9

5

3

2

2

1

1

1

1

1

1

1

1

1

1
AA 31-130

Réactivité croisée

Humain, Souris, Rat

Homologie

Dog,Cow,Pig,Horse

Purification

Purified by Protein A.

Immunogène

KLH conjugated synthetic peptide derived from human MDC1

Isotype

IgG
anti-Mdc1 (MDC1) (AA 1-100) antibody
MDC1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Mdc1 (MDC1) antibody
MDC1 Reactivité: Humain WB, IF, IHC (p), ICC Hôte: Lapin Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 31-130) antibody
MDC1 Reactivité: Humain, Souris, Rat WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated

anti-Mdc1 (MDC1) (AA 1-350) antibody
MDC1 Reactivité: Humain WB, IHC, IF Hôte: Lapin Polyclonal unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 unconjugated

anti-Mdc1 (MDC1) (N-Term) antibody (HRP)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 HRP

anti-Mdc1 (MDC1) (N-Term) antibody (FITC)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 FITC

anti-Mdc1 (MDC1) (N-Term) antibody (Biotin)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 Biotin

anti-Mdc1 (MDC1) (N-Term) antibody (PE)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 PE

anti-Mdc1 (MDC1) (N-Term) antibody (APC)
MDC1 Reactivité: Souris WB, IF, ICC Hôte: Souris Monoclonal P2B11 APC

Indications d'application

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur

ProClin

Précaution d'utilisation

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption

12 months
Antigène

MDC1 (Mdc1 (MDC1))

Autre désignation

Mdc1

Sujet

Synonyms: NFBD1, Mediator of DNA damage checkpoint protein 1, Nuclear factor with BRCT domains 1, MDC1, KIAA0170
Background: Required for checkpoint mediated cell cycle arrest in response to DNA damage within both the S phase and G2/M phases of the cell cycle. May serve as a scaffold for the recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage marked by 'Ser-139' phosphorylation of histone H2AFX. Also required for downstream events subsequent to the recruitment of these proteins. These include phosphorylation and activation of the ATM, CHEK1 and CHEK2 kinases, and stabilization of TP53 and apoptosis. ATM and CHEK2 may also be activated independently by a parallel pathway mediated by TP53BP1.

ID gène

9656

UniProt

Q14676

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