Recombinant CDC25C anticorps

N° du produit ABIN7828098

Cet anticorps anti-CDC25C Monoclonal Lapin (Clone A595) (ABIN7828098) détecte spécifiquement CDC25C dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Recombinant CDC25C anticorps (ABIN7828098)

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp CDC25C est non-conjugé

Application: Western Blotting (WB)

Clone: A595

Détail du produit anti-CDC25C anticorps

Fonction: Recombinant Cdc25C Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human Cdc25C fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur CDC25C

Antigène: CDC25C (Cell Division Cycle 25 Homolog C (S. Pombe) (CDC25C))

Autre désignation: Cdc25C

Sujet: CDC,PPP1R,CDC25C,CDC25,PPP1R60,Cdc25C is a protein phosphatase responsible for dephosphorylating and activating cdc2, a crucial step in regulating the entry of all eukaryotic cells into mitosis. Cdc25C is constitutively phosphorylated at Ser216 throughout interphase by c-TAK1, while phosphorylation at this site is DNA damage-dependent at the G2/M checkpoint. When phosphorylated at Ser216, Cdc25C binds to members of the 14-3-3 family of proteins, sequestering Cdc25C in the cytoplasm and thereby preventing premature mitosis. The checkpoint kinases Chk1 and Chk2 phosphorylate Cdc25C at Ser216 in response to DNA damage. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 53 kDa

Observed MW: 53 kDa

UniProt: P30307

Pathways: Cycle Cellulaire, M Phase