Recombinant PIK3R1 anticorps

N° du produit ABIN7828456

Cet anticorps Lapin Monoclonal détecte spécifiquement PIK3R1 dans IHC et IF. Il présente une réactivité avec des échantillons de Humain et Souris.

Aperçu rapide pour Recombinant PIK3R1 anticorps (ABIN7828456)

Antigène: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PIK3R1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Clone: A332

Détail du produit anti-PIK3R1 anticorps

Fonction: Recombinant PI3 Kinase p85 alpha Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human PI3 Kinase p85 alpha fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: IHC 1:50-1:100,IF 1:50

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur PIK3R1

Antigène: PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Autre désignation: PI3 Kinase p85 alpha

Sujet: GRB,IMD,AGM,PIK3R,AGM7,GRB1,IMD36,p85,p85-ALPHA,PI3 Kinase p85 alpha,PIK3R1,p85 alpha,P85A,Phosphatidylinositol 3 kinase,Phosphatidylinositol 3 kinase associated p 85 alpha,Phosphatidylinositol 3 kinase regulatory 1,Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha,Phosphatidylinositol 3-kinase regulatory subunit alpha,Phosphoinositide 3 kinase,PI3 kinase p85 subunit alpha,PI3K,PI3K regulatory subunit alpha,PI3-kinase regulatory subunit alpha,PI3-kinase subunit p85-alpha,polypeptide 1 (p85 alpha),PtdIns 3 kinase p85 alpha,PtdIns-3-kinase regulatory subunit alpha,PtdIns-3-kinase regulatory subunit p85-alpha,regulatory subunit,regulatory subunit 1 (alpha),Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin-dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

UniProt: P27986

Pathways: TCR Signaling, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, L'effet Warburg