Recombinant TGFB1 anticorps

N° du produit ABIN7828634

L’anticorps anti-TGFB1 Monoclonal Lapin est utilisé pour la détection de TGFB1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB et IHC.

Aperçu rapide pour Recombinant TGFB1 anticorps (ABIN7828634)

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: A618

Détail du produit anti-TGFB1 anticorps

Fonction: Recombinant TGF beta 1 Monoclonal Antibody

Purification: Protein A purified

Immunogène: Recombinant human TGF beta 1 fragment

Isotype: IgG, kappa

Information d'application

Indications d'application: WB 1:1000,IHC 1:500-1:1000

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 % protein protectant.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Date de péremption: 12 months

Détails sur TGFB1

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Autre désignation: TGF beta 1

Sujet: DPD,Transforming growth factor beta,TGF-B,TGFB1,CED,DPD1,LAP,TGFB,TGFbeta,TGF-β,Cartilage-inducing factor,Differentiation inhibiting factor,IBDIMDE,TGF-B1,TGF-beta 1,TGF-beta-1,TGF-β1,Transforming growth factor beta-1 proprotein,Latency-associated peptide,Transforming growth factor beta-1,beta 1,Prepro transforming growth factor beta 1,TGF beta,TGF beta 1,TGF beta 1 protein,Tgfb-1,TGF-beta 1 protein,TGFbeta1,TGF-beta1,TGF-beta-5,transforming growth factor,Transforming Growth Factor b1,Transforming Growth Factor beta 1,Transforming growth factor beta 1a,Transforming Growth Factor-1,Transforming growth factor-β (TGF-β) superfamily members are critical regulators of cell proliferation and differentiation, developmental patterning and morphogenesis, and disease pathogenesis. TGF-β elicits signaling through three cell surface receptors: type I (RI), type II (RII), and type III (RIII). Type I and type II receptors are serine/threonine kinases that form a heteromeric complex. In response to ligand binding, the type II receptors form a stable complex with the type I receptors allowing phosphorylation and activation of type I receptor kinases. The type III receptor, also known as betaglycan, is a transmembrane proteoglycan with a large extracellular domain that binds TGF-β with high affinity but lacks a cytoplasmic signaling domain. Expression of the type III receptor can regulate TGF-β signaling through presentation of the ligand to the signaling complex. The only known direct TGF-β signaling effectors are the Smad family proteins, which transduce signals from the cell surface directly to the nucleus to regulate target gene transcription. Cat.No. Product Name Clone No. IF:{{item.impact}} Journal:{{item.journal}} ({{item.year}}) DOI:{{item.doi}} Reactivity:{{item.species}} Sample Type:{{item.sample_type}} Previous {{ page }} Next Q{{(FAQpage.currentPage - 1)*pageSize+index+1}}:{{item.name}} Previous {{ page }} Next [

Poids moléculaire:

Calculated MW: 44 kDa

Observed MW: 44, 10 kDa The actual band is not consistent with the expectation.

UniProt: P01137

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints