Recombinant IGF1R anticorps

N° du produit ABIN7851151

Cet anticorps anti-IGF1R Chimeric Human (Clone DMC721) (ABIN7851151) détecte spécifiquement IGF1R dans FACS. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant IGF1R anticorps (ABIN7851151)

Antigène: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Type d'anticorp: Recombinant Antibody

Fragment: Fc fragment

Reactivité: Humain

Hôte: Human, Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp IGF1R est non-conjugé

Application: Flow Cytometry (FACS)

Clone: DMC721

Détail du produit anti-IGF1R anticorps

Fonction: Anti-IGF-1R antibody(DMC721), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Flow Cyt 1/100

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Please see Certificate of Analysis for specific instructions of reconstitution.

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détails sur IGF1R

Antigène: IGF1R (Insulin-Like Growth Factor 1 Receptor (IGF1R))

Autre désignation: IGF-1R

Sujet: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]

UniProt: P08069

Pathways: Signalisation RTK, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Autophagy