CD11b anticorps (Activation Site) (FITC)
Aperçu rapide pour CD11b anticorps (Activation Site) (FITC) (ABIN7830274)
Antigène
Voir toutes CD11b (ITGAM) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Activation Site
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Fonction
- Anti-Hu CD11b (activation epitope) FITC
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Attributs du produit
- The mouse monoclonal antibody CBRM1/5 recognizes an activation-dependent epitope on extracellular part of CD11b (Mac-1alpha), a 165-170 kDa type 1 transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells. The antibody recognizes a subset of CD11b molecules on neutrophils and monocytes activated with chemoattractants or phorbol esters and it does not recognize CD11b on non-activated cells.
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Purification
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Isotype
- IgG1, kappa
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Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze,Protect from prolonged exposure to light
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Autre désignation
- CD11b
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Sujet
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NCBI Full Gene Name: integrin subunit alpha M
Other names: Mac-1, Integrin alpha M, ITGAM, CR3A, MO1A, MAC1A
Gene name: ITGAM
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ID gène
- 3684
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UniProt
- P11215
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Pathways
- Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Antigène
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