Recombinant Ret Proto-Oncogene anticorps (C-Term)

N° du produit ABIN7857694

Cet anticorps anti-Ret Proto-Oncogene Monoclonal Souris (Clone r3F8) (ABIN7857694) détecte spécifiquement Ret Proto-Oncogene dans IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Recombinant Ret Proto-Oncogene anticorps (C-Term) (ABIN7857694)

Antigène: Ret Proto-Oncogene (RET)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ret Proto-Oncogene est non-conjugé

Application: Immunohistochemistry (IHC)

Clone: R3F8

Détail du produit anti-Ret Proto-Oncogene anticorps

Épitope: C-Term

Expression System: CHO Cells

Fonction: Recombinant RET Proto-oncogene (Medullary Thyroid Carcinoma Marker) Antibody

Specificité: The ret-proto-oncogene encodes a cell surface glycoprotein belonging to the tyrosine-kinase receptor family. Three main splice variants have been identified. Immunoreactivity of the ret-proto-oncogene in normal tissue has been found in Schwann cells, sympathetic ganglion, adrenal medulla, astrocytes and cortical neurons.

Purification: 200ug/ml of Ab produced in CHO cell mammalian-based expression system.

Immunogène: Prokaryotic recombinant fusion protein corresponding to the extreme C-terminal cytoplasmic region of the human ret oncoprotein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Prepared in 10  mM PBS

Agent conservateur: Azide free

Stock: -20 °C,-80 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur Ret Proto-Oncogene

Antigène: Ret Proto-Oncogene (RET)

Autre désignation: RET Proto-oncogene

Sujet:

Cadherin family member 12 (CDHF12), Cadherin related family member 16 (CDHR16), ELKS, HSCR1, Hydroxyaryl protein kinase, MEN2A, MEN2B, MTC1, Multiple endocrine neoplasia and medullary thyroid carcinoma 1, Oncogene RET, Proto-oncogene c-Ret, Proto-oncogene tyrosine-protein kinase receptor ret, PTC, RET, RET ELE1, RET51, RET9

Human brain, breast, colon or prostate carcinoma.

Poids moléculaire: 150kDa (precursor), 170kDa (Mature)

ID gène: 5979, 350321

UniProt: P07949

Pathways: Signalisation RTK, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation