FGF23 anticorps (AA 25-251)

N° du produit ABIN7863533

Cet anticorps Souris Monoclonal détecte spécifiquement FGF23 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour FGF23 anticorps (AA 25-251) (ABIN7863533)

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FGF23 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: FGF23-4163

Détail du produit anti-FGF23 anticorps

Épitope: AA 25-251

Fonction: FGF23 (Fibroblast Growth Factor 23) Antibody

Specificité: Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55 % amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant fragment (around aa25-251) of human FGF23 protein (exact sequence is proprietary)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur FGF23

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Autre désignation: FGF23

Sujet:

ADHR, FGF-23, FGFN, Fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, Tumor-derived hypophosphatemia-inducing factor

Human kidney tissue.

Poids moléculaire: 12-32kDa

ID gène: 8074, 287370

UniProt: Q9GZV9

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion