IFNA anticorps

N° du produit ABIN7862971

Cet anticorps Souris Monoclonal détecte spécifiquement IFNA dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour IFNA anticorps (ABIN7862971)

Antigène: IFNA (Interferon alpha (IFNA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNA est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: IFNA-6689

Détail du produit anti-IFNA anticorps

Fonction: Interferon alpha Antibody

Specificité: This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- & Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.Produced by macrophages, IFN-alphas have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: Recombinant human IFNA1 protein

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Date de péremption: 24 months

Détails sur IFNA

Antigène: IFNA (Interferon alpha (IFNA))

Autre désignation: Interferon alpha

Sujet:

IFN alpha, IFN alpha 1/13, IFN alpha 1b, Interferon alpha 13 (IFNA13), Interferon alpha leukocyte (IFL), Interferon alpha-1/13 (IFN-alpha-1/13), Interferon alpha-D (IFN alphaD), Interferon alpha1 (IFNA1), LeIF D

Stimulated human peripheral blood mononuclear cells

Poids moléculaire: 16-27kDa

ID gène: 3439

UniProt: P01562

Pathways: Signalistation JAK/STAT, Signalisation TLR, Hepatitis C, Inflammasome