YY1 anticorps

N° du produit ABIN7863950

Cet anticorps Souris Monoclonal détecte spécifiquement YY1 dans WB et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour YY1 anticorps (ABIN7863950)

Antigène: YY1 (YY1 Transcription Factor (YY1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp YY1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: YY1-5436

Détail du produit anti-YY1 anticorps

Fonction: YY1 (Transcription Factor) Antibody

Specificité: The YY1 transcription factor, also known as NF-E1 (human) and Delta or UCRBP (mouse) is of interest due to its diverse effects on a wide variety of target genes. YY1 is broadly expressed in a wide range of cell types and contains four C-terminal zinc finger motifs of the Cys-Cys-His-His type and an unusual set of structural motifs at its N-terminal end. It binds to downstream elements in several vertebrate ribosomal protein genes, where it apparently acts positively to stimulate transcription and can act either negatively or positively in the context of the immunoglobulin k 3' enhancer and immunoglobulin heavy-chain 79oΩE1 site as well as the P5 promoter of the adenoassociated virus. It thus appears that YY1 is a bifunctional protein, capable of functioning as an activator in some transcriptional control elements and a repressor in others.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogène: His-tagged YY1 protein

Isotype: IgG2, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Détails sur YY1

Antigène: YY1 (YY1 Transcription Factor (YY1))

Autre désignation: YY1

Sujet:

CF1, Delta transcription factor, INO80 complex subunit S, NF E1, NFE1, Transcriptional repressor protein YY1, UCR motif DNA binding protein, UCRBP, Yin and yang 1, Yin and Yang 1 protein, YY-1, YY1 transcription factor

Human kidney|tonsil or cervix carcinoma tissues

Poids moléculaire: 40/68kDa

ID gène: 7528, 388927

UniProt: P25490