CD8B anticorps
Aperçu rapide pour CD8B anticorps (ABIN7865609)
Antigène
Voir toutes CD8B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- anti-CD8b mouse monoclonal, EBS-CD-007, purified
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Purification
- affinity chromatography
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Immunogène
- human PBL
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Isotype
- IgG1 kappa
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Indications d'application
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ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)
FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 100 μg/mL
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Buffer
- PBS with 0.02 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- store at 2 - 8 °C
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- CD8B (CD8b Molecule (CD8B))
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Autre désignation
- CD8b
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Sujet
- EBS-CD-007 recognized a protein of 32 kDa, identified as CD8b. The CD8 Molecule consists of α and β chains, which are disulphide-linked into heterodimers or homodimers. CD8 is expressed on a T-cell subset (cytotoxic-suppressor T-cells), thymocytes and NK cells. The majority of CD8+ T-cells express CD8 as heterodimer. Some subpopulation of CD8+ T-cells as well as NK-cells may express homodimer. CD8 functions as a co-receptor is concert with TCR for binding the MHC class I/peptide complex. HIV-2 envelope glycoprotein binds CD8 α chain but not β chain. Positive control: HuT78 or hPBL. tonsil.
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Pathways
- TCR Signaling
Antigène
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