MALT1 anticorps

N° du produit ABIN7865701

Cet anticorps anti-MALT1 Monoclonal Souris (Clone EBS-T-007) (ABIN7865701) détecte spécifiquement MALT1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour MALT1 anticorps (ABIN7865701)

Antigène: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MALT1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: EBS-T-007

Détail du produit anti-MALT1 anticorps

Fonction: anti-MALT1 mouse monoclonal, EBS-T-007, purified

Purification: affinity chromatography

Immunogène: human MALT1 recombinant protein

Isotype: IgG1 kappa

Information d'application

Indications d'application:

IHC-paraffin_dilution: 1:50-1:100 (1-2 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)

WB_dilution: 1:50-1:100 (1-2 μg/mL)

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: store at 2 - 8 °C

Détails sur MALT1

Antigène: MALT1 (Mucosa Associated Lymphoid Tissue Lymphoma Translocation Gene 1 (MALT1))

Autre désignation: MALT1

Sujet: EBS-T-007 reacts with paracaspase MALT1, crucial for B- and T-cell activation/proliferation and activation of transcription factor NF-kappaB. It has an N-terminal death domain, two central immunoglobulin-like domains involved in the binding to the B-cell lymphoma 10 (BCL10) protein and a caspase-like domain. MALT1 and BCL10, can both be found translocated in MALT lymphoma. In such cases either BCL10 or MALT1 or both are highly expressed, depending on the site of translocation. Normal cells and MALT lymphomas lacking translocations exhibit much lower levels of expression. Positive control: HepG2 cells or lymphoma.

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteins