Recombinant HBEGF anticorps (PE)

N° du produit ABIN7867302

L’anticorps anti-HBEGF Chimeric Lapin est utilisé pour la détection de HBEGF dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour Recombinant HBEGF anticorps (PE) (ABIN7867302)

Antigène: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp HBEGF est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: DMC500

Détail du produit anti-HBEGF anticorps (PE)

Fonction: PE-conjugated Anti-HBEGF antibody(DMC500), IgG1 Chimeric mAb

Purification: Purified from cell culture supernatant by affinity chromatography

Isotype: IgG1

Information d'application

Indications d'application: Flow Cyt 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Liquid PBS with 0.05 %  Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2°C-8°C for 6 months

Date de péremption: 6 months

Détails sur HBEGF

Antigène: HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

Autre désignation: HBEGF

Sujet:

Synonyms: DTR, DTS, DTSF, HEGFL

Target Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor:EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB:Swiss-Prot Function]

UniProt: Q99075

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway