FGF23 anticorps (AA 1-251)

N° du produit ABIN7868968

Cet anticorps anti-FGF23 Monoclonal Souris (Clone FGF23-6371) (ABIN7868968) détecte spécifiquement FGF23 dans IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour FGF23 anticorps (AA 1-251) (ABIN7868968)

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FGF23 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: FGF23-6371

Détail du produit anti-FGF23 anticorps

Épitope: AA 1-251

Fonction: FGF23 Antibody / Fibroblast Growth Factor 23 (azide and preservative free)

Purification: Protein A/G affinity

Immunogène: A recombinant partial protein sequence (within amino acids 1-251) from the human protein was used as the immunogen for the FGF23 antibody.

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Optimal dilution of the FGF23 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Aliquot the FGF23 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Détails sur FGF23

Antigène: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Autre désignation: FGF23

Sujet: Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55 % amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

UniProt: Q9GZV9

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion