GADD45A anticorps (AA 1-30)
Aperçu rapide pour GADD45A anticorps (AA 1-30) (ABIN7869090)
Antigène
Voir toutes GADD45A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-30
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Fonction
- GADD45A Antibody
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Purification
- Purified
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Immunogène
- A portion of amino acids 1-30 from the human protein was used as the immunogen for the GADD45A antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the GADD45A antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Aliquot the GADD45A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
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Autre désignation
- GADD45A
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Sujet
- GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45A gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms.
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UniProt
- P24522
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Pathways
- Signalisation p53, Cycle Cellulaire
Antigène
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